5 jul. 1- Dados os compostos de Grignard abaixo, forneça a nomenclatura de cada um deles: a) H3C — CH2— CH2— CH2— MgCl Cloreto de butil-. Keywords: allylic oxidation, selenium dioxide, homoallylic alcohols, Grignard adsorvido em SiO2, propicia uma rota conveniente para tais compostos. O primeiro estudo sistemático sobre os compostos organoestânicos (OTs, .. tetrassubstituído via reação de “Grignard” (brometo ou cloreto de etil, butil ou.
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The occurrence and the effects of organotin compounds OTs have been studied since ocmposto long time, due to their widespread use and deleterious effects. The organic layer was washed with two portions of brine then dried with anhydrous MgSO 4.
The extracts were dried over MgSO 4filtered and the solvent was removed under reduced grignagd by rotatory evaporation.
The mixture dde stirred at ambient temperature for 8 h and then diluted with 30 mL of ether. The ether phase was washed with water 30 mLthen with brine 2×30 mLdried over MgSO 4filtered and the solvent was removed under reduced pressure by rotatory evaporation.
Emo consumo de OTs era estimado em cerca de toneladas por ano 3.
This result was still not satisfactory so we tried a different approach. How to cite this article. The same procedure as employed for the oxidation of 1 was used, starting with 7 3.
In brief, comlosto optimized a selective oxidation of allylic methyl groups in geraniol derivatives over a solid support to the corresponding trans- ab -unsaturated alcohols and aldehydes, using selenium dioxide and t -butylhydroperoxide adsorbed on silica gel as oxidants. Preparation of aromatic geraniol analogues via a Cu I -mediated Grignard coupling. Environmental contamination for organotin trignard. The Sharpless conditions for oxidation of geranyl acetate employs 0.
After the temperature reached room temperature, CuI 1.
Difunctional allylic terpenes are important synthetic building blocks. In a three necked round bottom flask, tert -butyldimethylsilyl 2-iodophenol ether 11 3. After stirring for 15 min at room temperature, cold pentane 25 mL was added, and the organic layer was washed with cold water, extracted with pentane 2×25 mL and then washed with brine.
New York,vol. Then a solution of 2 E – 3,7-dimethyl-2,6-octadienyl tetrahydro-2 H pyranyl ether 12 The mixture was treated drop wise with cold metanol 1 mL and extracted with hexane. Further studies on phenolic oxidation of these synthetic intermediates to achieve the synthesis of cyclic isoprenoids will be reported in due course.
To a solution of 10 3. Economic Entomology81 A new sequence was investigated with another substrate in an attempt to improve the yield of the desired phenol-alcohol 9 Scheme 4. To a stirred solution of 14 3.
To a solution of 2-iodophenol 2. Services on Demand Journal. C -geranyl and C -farnesyl phenols have been prepared by reaction of geranyl or farnesyl bromide with the sodium salt of the phenol.
To a two-necked mL round bottom flask with 2-iodophenyl tetrahydropyranyl ether 6 3.
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Also, we developed an efficient synthesis of 2-geranylphenol derivatives via a Cu I -mediated Grignard coupling of 2-lithiophenols and geranyl substrates.
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. The same procedure composo for the allylic oxidation of 1 was used; compound 8 2. After allowing the reaction mixture to reach ambient temperature, CuI was added followed by the addition of allylic alcohol 2. To stirred solution of 1. Economic Entomology79 Tetrahydro-2 H pyranyl ether 7 3. Conclusion In brief, we optimized a selective oxidation of allylic methyl groups in geraniol derivatives over a solid support to the corresponding trans- ab -unsaturated alcohols and aldehydes, using selenium dioxide and t -butylhydroperoxide adsorbed on silica gel as oxidants.
The chosen protecting groups clearly influence the oxidation process. The same procedure as employed for the grignsrd of 11 and 12 was usedstarting with tert -butyldimethylsilyl gfignard ether 11 3.
A solution of 2. How to cite this article. Bromination of geraniol 15 with phosphorus tribromide 0. The extracts were washed with a saturated aqueous solution of FeSO 4. Introduction A wide variety of phenolic natural products contain isoprenoid d. Also, an efficient synthesis of 2-geranylphenol derivatives via a Cu I -mediated Grignard coupling of 2-lithiophenols and geranyl substrates was developed.
In this work we reported a revision study on the history of Compoato and the techniques developed for its assessment and control. Services on Demand Journal. The mixture was stirred for 48 h. Em Organotin Compounds ; Sawyer, A.